6/30/2023 0 Comments Similarity sequences mathpercentage of the length of the sequence that is effectively aligned). Different criteria can be used, separately or in combination (percentage of identity, alignment score or E-value, alignment coverage i.e. The choice of the sequence similarity criteria that is used to infer homology is therefore an essential parameter of the single-linkage clustering approach. The principle of the single-linkage clustering is that if sequence A is considered homologous to sequence B, and B homologous to C, then A, B and C are grouped into the same family, whatever the level of similarity between A and C. Modelling Single linkage and filtering with alignment coverage constraints We discuss the interest of SiLiX for the clustering of homologous sequences in huge datasets, possibly in combination with other clustering methods. Moreover, it allows a satisfying quality of clustering. SiLiX outperforms other existing software programs both in terms of speed and memory requirements. Our approach presents several advantages over other clustering algorithms: it is extremely fast, it requires only limited memory and can be run on a parallel architecture - which is essential for ensuring its scalability to large datasets. We evaluated the computational performances and scalability of this method on a very large dataset of more than 3 millions sequences from the HOGENOM phylogenomic database. Finally, we adopt a divide-and-conquer strategy to deal with the quantity of data and design a parallel algorithm whose theoretical complexity is addressed in this paper. This approach enables also an incremental procedure where sequences and similarities are added into the dataset so that it would not be necessary to rebuild the families from scratch. To overcome memory limitations we follow an online framework in which we visit the edges one at a time to update the families dynamically. We model the dataset as a similarity network where sequences are vertices and similarities are edges. In this paper, we present a new approach for the clustering of homologous sequences, based on single transitive links ( single linkage) with alignment coverage constraints and implemented in a software package (called SiLiX for SIngle LInkage Clustering of Sequences). With the recent progress of sequencing technologies, there is an urgent need to prepare for the deluge and hence to develop methods able to deal with a huge quantity of sequences. The building of such phylogenomic databases involves three steps that require important computing resources: 1) compare all proteins to each other to detect sequence similarities, 2) cluster homologous sequences into families (that we will call the clustering step) and 3) compute multiple sequence alignments and phylogenetic trees for each family. Thanks to the progress of sequencing projects, this comparative approach can now be applied at the whole genome scale in many different taxa, and several databases have been developed to provide a simple access to collections of multiple sequence alignments and phylogenetic trees. The comparison of homologous sequences and the analysis of their phylogenetic relationships provide very useful information regarding the structure, function and evolution of genes. In contrast to geometric sequence, the new term is found by multiplying or dividing a fixed value from the previous term.Proteins can be naturally classified into families of homologous sequences that derive from a common ancestor. The new term in an arithmetic sequence is obtained by adding or subtracting a fixed value from the previous term.The sequence is said to be geometric when there is a common ratio between succeeding terms, indicated by ‘r.’ When there is a common difference between subsequent terms, represented as ‘d,’ a series can be arithmetic.Geometric Sequence is a series of integers in which each element after the first is obtained by multiplying the preceding number by a constant factor. An arithmetic Sequence is a set of numbers in which each new phrase differs from the previous term by a fixed amount.ISRO CS Syllabus for Scientist/Engineer Exam.ISRO CS Original Papers and Official Keys.GATE CS Original Papers and Official Keys.DevOps Engineering - Planning to Production.Python Backend Development with Django(Live).Android App Development with Kotlin(Live).Full Stack Development with React & Node JS(Live).Java Programming - Beginner to Advanced.Data Structure & Algorithm-Self Paced(C++/JAVA).Data Structures & Algorithms in JavaScript.Data Structure & Algorithm Classes (Live).
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6/30/2023 0 Comments Recentapps registry forensicsSpecifically, we perform forensics on 1.52 GB of Windows registry data collected from four computers and show that the proposed algorithms can reduce the processing time by up to approximately 3.31 times, as we increase the number of CPUs from 1 to 8 and the number of worker nodes from 2 to 8. Through extensive experiments using eight nodes in an actual distributed environment, we demonstrate that the proposed method can perform forensics efficiently on large-scale registry data. Third, we propose a distributed algorithm for each defined forensic scenario using Apache Spark operations. Second, we propose an algorithm to load the Windows registry into the Hadoop distributed file system (HDFS) for subsequent forensics. First, we define three main scenarios in which we classify the existing registry forensic studies into them. To this end, we devise distributed algorithms to analyze large-scale registry data collected from multiple Windows systems on the Apache Spark framework. However, it is a critical issue to analyze large-scale registry data collected from several Windows systems because it allows us to detect suspiciously changed data by comparing the Windows registry in multiple systems. Because the Windows registry depends on the system on which it operates, the existing forensic methods on the Windows registry have been targeted on the Windows registry in a single system. In this study, we investigate large-scale digital forensic investigation on Apache Spark using a Windows registry. 6/30/2023 0 Comments Convert picture to passport sizeUntil the early 2000s, antiemetics including promethazine, metoclopramide and prochlorperazine were widely used in children, however their use is now controversial due to reports of adverse events including sedation and extrapyramidal reactions. Nausea and vomiting resulting from acute gastroenteritis is particularly challenging in children. Therapeutic options available for adults with vomiting secondary to gastroenteritis include dopamine antagonists such as metoclopramide or prochlorperazine and serotonin antagonists such as ondansetron. Table 2 - Indications and scheduling for antiemetic drugsĪcute gastroenteritis is caused by viral, bacterial or protozoal infections. † Not currently registered as antiemetics in Australia * Also block serotonin, histamine, adrenergic and muscarinic receptors When combined with 5-HT 3 antagonists there are reduced serotonin concentrations in the gut and increased sensitivity of 5-HT 3 receptors to antiemetics.Īgonist action at the GABA A receptor provides anxiolysis.Īction at the chemoreceptor trigger zone to suppress the activity of dopamine.Īctivate cannabinoid CB1 (inhibitory) receptors in the central nervous system and peripheral nervous system to modulate release of neurotransmitters. Hyoscine (oral) – available as non-prescription medicine.Ĭentral inhibition of prostaglandin synthesis and encephalin release. Hyoscine (parenteral) – palliative care medicine. Promethazine also blocks dopamine D2 receptors.īlock muscarinic receptors in vestibular nuclei, vomiting centre and higher brain centres. Netupitant/palonosetron fixed-dose combinationīlock neurokinin type 1 receptors in the central and peripheral nervous system.Ĭyclizine, doxylamine, promethazine and pheniramine all block muscarinic receptors. Tropisetron – chemotherapy-induced nausea and vomiting Palonosetron – chemotherapy-induced nausea and vomiting Granisetron – chemotherapy or radiation- induced nausea and vomiting Ondansetron – chemotherapy or radiation- induced nausea and vomiting Metoclopramide and paracetamol combinations – available as non-prescription medicinesīlock 5-HT 3 receptors in the chemoreceptor trigger zone and gastrointestinal tract. Metoclopramide (parenteral) – palliative care medicine These include blockade of serotonin, histamine, adrenergic and muscarinic receptors. Phenothiazines – prochlorperazine,* chlorpromazine*īutyrophenones – droperidol,* haloperidol*īlock dopamine type 2 (D2) receptors centrally in the chemoreceptor trigger zone and peripherally in the gastrointestinal tract.ĭomperidone blocks peripheral D2 receptors only.Īt higher doses, effects on other receptors are seen. Pharmaceutical Benefits Scheme restrictions Table 1 - Antiemetics available in Australia 6/30/2023 0 Comments Give up robot html5And the best part is, everything takes place within the realm of the imagination. The characters’ collective decisions and storytelling make up the overarching series of adventures. The length of a campaign depends entirely on the decision of the players.Įach character gets a turn at developing the storyline much farther. A single campaign can last for a single session, an entire month, or even years. This ongoing series of adventures and conquests comprise a campaign. Once you complete a story or a quest, another one can begin. Each time the characters have taken their turn, the DM sets the stage for new adventures and plot points. It also pushes the storyline towards greater adventures. These abilities help them to develop their characters. It’s also the means by which characters gain points to stay alive and to acquire new abilities. The rolling of the dice determines the success or failure of any decision or action made. In cases where the outcome of an action is uncertain, the game relies on the rolling of a dice. The characters then get the opportunity to select their own course of action at every turn. To set the game in the right direction, the DM must provide opportunities for group exploration, conversation, and discovery. The game centers on three broad categories of activity: exploration, interaction, and combat. How Does Dungeons and Dragons Gameplay Work? Photo by cdn.mmos Ideally, a party of adventurers is one where characters complement each other. Every character is different, with various strengths and weaknesses that need consideration. The players then get to create their own characters by following the parameters in the Dungeons and Dragons guidebook. They set the premise, descriptive location, and challenges for the players. A Dungeon Master (DM) acts as the main storyteller and person of authority over the campaign. With a polyhedral die and a large map for reference, the characters are able to navigate the game. The game is usually referred to as a “tabletop” game because it’s traditionally played with all the players sitting in one table. And the outcomes of the story are largely determined by the decisions of the characters. Players roll dice to resolve whether they hit or miss their intended action. But unlike childhood games of make-believe, D&D games have a semblance of structure to the stories. It also posits how a fantasy adventurer might react to each series of challenges. It’s about picturing a kingdom filled with elves, giants, and anything else you can imagine. Like those games, this game is largely driven by one’s imagination. The game shares traditional elements with childhood games of make-believe. The game revolves around creating worlds of swords, magic and adventures done by means of structured storytelling. Dungeons and Dragons, affectionately called D&D by fans, is a high-fantasy roleplaying game. 6/30/2023 0 Comments Hard drive with sd card readerA built-in SD card reader allows fast media offloads, giving you the freedom to transfer large quantities of photos and videos while on the go without the need for a laptop. WD My Passport Wireless is an external hard drive equipped with an SD 3.0 card reader. This drive allows me to take long photography trips without bringing my laptop with me. It has an internal battery and a dedicated SD memory card reader that automatically backs up the contents of the memory cards to the internal drive. It does not exactly fit the requirements for a travel drive because it is bulky and much heavier, but it has two significant features that have drastically changed how I travel. I recently started to use an entirely different model from Western Digital. WD My Passport Wireless External HD with SD Card Reader The SanDisk Extreme Portable SSD is ruggedized, water- and dust-resistant, and features a solid-state design to ensure long-term reliability in the most demanding environments.Ĥ. With up to 4TB capacity, this portable SSD fits easily into your pocket or bag and features USB 3.1 interface Gen-2 (10Gb/s) and USB 2.0 compatibility. The SanDisk Extreme Portable SSD is the best external hard drive for photographers who travel. Plus, it is water-resistant, dust-resistant, and shock-resistant, a true dream for any traveling photographer. It is a low-power consumption, bus-powered model. It is an SSD drive, which means it is compact and has no moving parts. SanDisk Extreme is a true travel warrior external hard drive.
Golden State WarriorsSan Jose State University. Split up, and there's no telling what the future holds for both. Creative Content Coordinator, Premium Sales & Service at Golden State Warriors. Stay together, and they can at least hold out hope of contending next season. The Dubs desperately need Green, and you could argue the feeling is mutual. Lachlan Cunningham / Getty Images During the Golden State Warriors championship parade, Draymond Green took one last shot at his NBA Finals nemesis, Cleveland Cavaliers center Tristan. Maybe the contract wouldn't age the greatest on the back end, but if he exited, the impact of his loss would be immediate and profound. It's imperative to keep that value in mind when weighing the merits of giving a 33-year-old a lanky and pricey pact if (when?) he declines his $27.6 million player option for next season. Steph Curry, Steve Kerr, and the Golden State Warriors plan to bounce back in Game 2 of NBA Finals It was described as rough inside locker room after. Green's value runs the gamut from emotional leadership, dynamic defense and offensive quarterbacking. Browse Golden State Warriors Store for the latest Warriors Autographed Collectibles, Display Cases, Photos and more for men, women, and kids. is the Golden Snitch, and its the most important ball of the lot. Enjoy Quick Flat-Rate Shipping On Any Size Order. Andre Iguodala 9, Draymond Green 23, Klay Thompson 11 and Stephen Curry 30 of the Golden State Warriors pose for a photo after defeating the Boston Celtics 103-90 in Game Six of the 2022 NBA. While Quidditch was the first (and so far, only) broomstick-based game to. He's that important to winning, to who we are." Golden State Warriors Photos at the Official Online Store of the Warriors. 12 acres of vacant property, located within the Mission Bay South Redevelopment Plan (MBSRP). "If Draymond's not back, we're not a championship contender," Warriors coach Steve Kerr told reporters. The Golden State Warriors (GSW) acquired from Inc. At the same time, there probably hasn't been enough talk about who the Warriors would be without him. Over the years, there have been countless debates about the kind of player Draymond Green would be outside of Golden State. Get special offers, deals, discounts & fast delivery options on. The improved recording codec enables you to capture screens at 30 fps and get smooth video with no out-of-sync problems. Shop Movavi Screen Capture 9 Pro Edition Download online at a best price in Bahrain. Grab the entire screen or adjust the capture area depending on the task. Movavi Screen Capture Pro 9.3 license: Shareware ( 49.95) downloads: 72. Movavi Screen Capture Pro - X 64-bit Download. 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6/29/2023 0 Comments Part 135 pilot jobs low timeHe served on the Apollo 13 accident investigation and on the Rogers Commission, which investigated the Space Shuttle Challenger disaster. President Jimmy Carter presented him with the Congressional Space Medal of Honor in 1978, he was inducted into the National Aviation Hall of Fame in 1979, and with his former crewmates received the Congressional Gold Medal in 2009.Īfter he resigned from NASA in 1971, Armstrong taught in the Department of Aerospace Engineering at the University of Cincinnati until 1979. Along with Collins and Aldrin, Armstrong was awarded the Presidential Medal of Freedom by President Richard Nixon and received the 1969 Collier Trophy. Kennedy "of landing a man on the Moon and returning him safely to the Earth" before the end of the decade. Apollo 11 was a major US victory in the Space Race, by fulfilling a national goal proposed in 1961 by President John F. When Armstrong first stepped onto the lunar surface, he famously said: "That's one small step for man, one giant leap for mankind." It was broadcast live to an estimated 530 million viewers worldwide. On July 20, 1969, Armstrong and Apollo 11 Lunar Module (LM) pilot Buzz Aldrin became the first people to land on the Moon, and the next day they spent two and a half hours outside the Lunar Module Eagle spacecraft while Michael Collins remained in lunar orbit in the Apollo Command Module Columbia. During training for Armstrong's second and last spaceflight as commander of Apollo 11, he had to eject from the Lunar Landing Research Vehicle moments before a crash. During this mission with pilot David Scott, he performed the first docking of two spacecraft the mission was aborted after Armstrong used some of his re-entry control fuel to stabilize a dangerous roll caused by a stuck thruster. He made his first spaceflight as command pilot of Gemini 8 in March 1966, becoming NASA's first civilian astronaut to fly in space. Air Force's Man in Space Soonest and X-20 Dyna-Soar human spaceflight programs.Īrmstrong joined the NASA Astronaut Corps in the second group, which was selected in 1962. He was the project pilot on Century Series fighters and flew the North American X-15 seven times. After the war, he completed his bachelor's degree at Purdue and became a test pilot at the National Advisory Committee for Aeronautics (NACA) High-Speed Flight Station at Edwards Air Force Base in California. He saw action in the Korean War, flying the Grumman F9F Panther from the aircraft carrier USS Essex. He became a midshipman in 1949 and a naval aviator the following year. Navy paying his tuition under the Holloway Plan. He entered Purdue University, studying aeronautical engineering, with the U.S. He was also a naval aviator, test pilot, and university professor.Īrmstrong was born and raised in Wapakoneta, Ohio. Neil Alden Armstrong (August 5, 1930 – August 25, 2012) was an American astronaut and aeronautical engineer who became the first person to walk on the Moon in 1969. For the second process, the ink was derived from pine wood from which the resin had been removed. A skillful artisan could tend to 200 lamps at once. The lampwick used in the making of lampblack was first soaked in the juice of Lithospermum officinale before burning. 30 grams) lampblack of fine quality could be produced from a catty (approx. For the first process, more than one ounce (approx. In the Chinese record Tiangong Kaiwu, ink of the period was said to be made from lampblack of which a tenth was made from burning tung oil, vegetable oils, or lard, and nine-tenths was made from burning pine wood. Inkmaking from pine wood, as depicted in the Tiangong Kaiwu (1637) It was made by combustion in lamps with wicks, using animal, vegetable, and mineral oils. From the Song dynasty onwards, lampblack also became a favored pigment for the manufacturing of black inks. 1600–1660) of the Ming dynasty has described the inkmaking process from pine soot in his work Tiangong Kaiwu. Several studies observed that 14th-century Chinese inks are made from very small and uniform pine soot in fact the inks are even superior in these aspects to modern soot inks. Pine soot was traditionally favored in Chinese inkmaking. In contrast to Chinese inks that were permanent, these inks could be washed away with water. Like Chinese black inks, the black inks of the Greeks and Romans were also stored in solid form before being ground and mixed with water for usage. To use the dry mixture, a wet brush would be applied until it rehydrated, or more commonly in East Asian calligraphy, a dry solid ink stick was rubbed against an inkstone with water. The traditional Chinese method of making ink was to grind a mixture of hide glue, carbon black, lampblack, and bone black pigment with a mortar and pestle, then pour it into a ceramic dish where it could dry. In India, the carbon black from which India ink is formulated was obtained indigenously by burning bones, tar, pitch, and other substances. The practice of writing with ink and a sharp-pointed needle in Tamil and other Dravidian languages was common practice from antiquity in South India, and so several ancient Buddhist and Jain scripts in India were compiled in ink. Indian documents written in Kharosthi with this ink have been unearthed in as far as Xinjiang, China. India ink has been in use in India since at least the 4th century BC, where it was called masi, an admixture of several substances. A cylindrical artifact made from black ink has been found in Qin tombs, dating back to the 3rd century BC during the Warring States or dynastic period, from Yunmeng, Hubei. Numerous documents written in ink on precious stones as well as bamboo or wooden tablets dating to the Spring and Autumn, Warring States, and Qin period have been uncovered. A considerable number of oracle bones of the late Shang dynasty contain incised characters with black pigment from a carbonaceous material identified as ink. India ink was first invented in China, but the English term India(n) ink was coined due to their later trade with India. Woods and Woods (2000) state that the process of making India ink was known in China as early as the middle of the 3rd millennium BC, in Neolithic China, whereas Needham (1985) states that inkmaking commenced perhaps as early as 3 millennia ago in China. If a binder is used, India ink may be waterproof or non-waterproof.Ī solid ink stick used for the preparation of ink India ink is commonly sold in bottled form, as well as a solid form as an inkstick (most commonly, a stick), which must be ground and mixed with water before use. A binding agent such as gelatin or, more commonly, shellac may be added to make the ink more durable once dried. No binder material is necessary: the carbon molecules are in colloidal suspension and form a waterproof layer after drying. In East Asian traditions such as ink wash painting and Chinese calligraphy, India ink is commonly used in a solid form called an inkstick.īasic India ink is composed of a variety of fine soot, known as lampblack, combined with water to form a liquid. It is commonly applied with a brush (such as an ink brush) or dip pen. India ink is also used in medical applications.Ĭompared to other inks, such as the iron gall ink previously common in Europe, India ink is noted for its deep, rich black. India ink ( British English: Indian ink also Chinese ink) is a simple black or coloured ink once widely used for writing and printing and now more commonly used for drawing and outlining, especially when inking comic books and comic strips. Example of India ink on paper, Zeedijk by Gustaaf Sorel, (1939) 6/29/2023 0 Comments Free android ps3 media serverYou can either drag folders into the list or click the + button to browse your folders in Finder. From here, you’ll need to tell Plex where your media is located. At the bottom left you should see + and – buttons. Click on it to access a drop down menu and then choose Plex Media Manager.Ī window will appear. MAC: After you’ve successfully installed the Plex Media Server, an icon in the shape of a black chevron should appear in your menu bar. This process differs a bit for Windows and Mac. Following installation you’ll need to add media to your library. The Plex Media Center is optional, but if you’re in the market for a new media center, it’s definitely worth a look.Īfter you’ve downloaded the Plex Media Server, click through all the necessary setup windows to install it. The important one is the Plex Media Server. You can do that here for OSX and here for Windows. Oh, and did we mention it’s free?įirst, you’ll need to download Plex. If you have media on either a Mac or a Windows computer (or both), we recommend Plex for its cross-platform compatibility, its clean and easily navigable interface and all the advanced connectivity features you can get. For instance, the PlayStation 3 doesn’t natively support playback of lossless FLAC files, but Plex will transcode them into other compatible formats on the fly.įor this particular tutorial, we used Plex. Plex and PS3 Media Server are two extremely popular packages that transcode file formats the PS3 doesn’t natively support. The latest version of Windows Media Player is generally the easiest option because it comes preinstalled with Windows, but a number of third-party applications also exist that offer better file compatibility and more advanced features. WINDOWS 7/Vista: Windows users have a number of useful options when it comes to serving media files from their PCs. This allows the PS3 to detect networked computers running Universal Plug and Play (UPnP) server software. Go into the PS3’s Settings menu and navigate to Network Settings – Media Server Connection, and select Enabled. This can be a lifesaver when you’re copying lots of files to your PS3 over a network. And if all your hardware supports it, switch to the 5GHz frequency band for a 60-100 percent speed bump and less interference. Adjust your router’s wireless settings to operate in 802.11n mode only. Extra Life: If your network consists exclusively of 802.11n-compatible hardware, bypass the PS3’s slower (802.11b/g) wireless connection by plugging it directly into your router or an extender (we used an Airport Express) via Ethernet cable. |